Speakers

Event Description

Blood cancers are characterized by disruption of the normal process of the hematopoietic system. Malignant cells occupy multiple differentiation states, with substantial heterogeneity within and between patients. One of the core drivers of this abnormal differentiation is a perturbation of the epigenetic landscape, resulting in altered gene regulatory potential. High throughput single cell genomics enables the mechanistic characterization of this aberrant differentiation, providing improved disease classification and identifying regulatory nodes that may be amenable to therapeutic inhibition. In this talk, Dr. Braun will discuss how he used scRNA, scATAC, and scMethylation profiling with ScaleBio products to study blood cancers. Dr. Khare will open the session with an introduction to ScaleBio’s portfolio for high throughput, single cell analysis at scale.